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At least 20% of PCI patients are High Bleeding Risk (HBR) where there is a need to avoid prolonged dual antiplatelet therapy (DAPT).1-9

The BioFreedomTM Drug-Coated Stent (DCS) is significantly safer and significantly more efficacious than a BMS in High Bleeding Risk patients, with a DAPT regime of only one month, the shortest DAPT regime mandated for all patients in a published, double-blind randomized controlled trial.10

By directly delivering BA9TM - an effective anti-restenotic therapy - without polymer or carrier, becoming a BMS at 28 days, the DAPT regime can be shortened when treating patients with the BioFreedom stent.10

 

BioFreedom HBR

In LEADERS FREE, High bleeding risk patients include, but are not exhaustively: Age >75 OACs, Renal Failure, planned surgery within the next 12 months, anemia of recent TF, Cancer, hospitalisation for bleeding, poor DAPT compliance, NSAIDS steroids, thrombocytopenia, stroke <1 year, severe liver disease, prior intracerebral bleed.

 

BioFreedom is now listed as stent of choice in ESC DAPT guidelines, for 1 month-ultra short DAPT in patients with stable CAD in whom longer DAPT regimes poses safety concerns*.

11523-000-EN - Rev.01 + 11524-000-EN - Rev.01
BioFreedom™
Movie - Who are HBR Patients?
BioFreedom™
HBR patients brochure

*European Heart Journal (2018)39, 213-254
1. Rao et al. AHJ 2013;166:273-281.e4
2. Rittger H et al. Herz 2014;39(2):212-8
3. Faxon et al. Circ Cardiovasc Interv 2011;4:522-34
4. De Biase et al. Transl Med 2015;11(3):14-23
5. To et al. Circ Cardiovasc Interv-2009;2:213-21
6. Wiviott et al. NEJM 2007;357:2001-15
7. Pilgrim et al. Circ Cardiovasc Interv. 2012;5:202-210
8. Shanmugam VB et al. Journal of Geriatric Cardiology 2015;12:174−184
9. Urban P. et al. Am Heart J 2013;165:704-9
10. Urban P et al. N Engl J Med 2015;373:2038-47

 

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