The primary end point of LEADERS FREE III was presented confirming the safety and efficacy of BioFreedom Ultra at PCR eCourse 
Blue Sail Medical and Biosensors International achieve a milestone towards entering the Structural Heart business, as they finalize the acquisition of Switzerland based NVT AG. 
LEADERS FREE pre-specified non-cardiac surgery subgroup presented at TCT . Published in 2020.
The primary end point of the Alpha registry was presented at EuroPCR . Published in 2020.
The primary end point of LEADERS FREE II was presented and confirmed the reproducibility of the LEADERS FREE results in a North American population at TCT . Published in 2020.
The primary endpoint of GLOBAL LEADERS was presented and confirmed the excellent safety of the BioMatrix DES at 2 years at ESC . Published in 2018.
LEADERS FREE Japan presented at CVIT and e-poster at EuroPCR. 
BioFreedom is launched in Japan. 
LEADERS FREE II completed enrolment of 1,200 patients in September. 
Primary endpoint of BioFreedom USA presented at AHA 2016, and CRT. . Published in 2017.
Launch of our first, cobalt chromium biodegradable polymer drug-eluting stent. 
FDA approves Leaders Free II which began enrolment in the USA and Europe. 
Several pre-specified subgroups of LEADERS FREE are presented and confirm that BioFreedom benefits all patient subgroups: Acute Coronary Syndrome (ACS) are Oral Anti Coagulant (OAC) are presented at EuroPCR and Elderly patients at ESC. . Published in 2017.
LEADERS FREE 2 year follow up is presented at TCT and confirms the long term benefit of BioFreedom over BMS in HBR patients with the absence of late catch-up. . Published in 2017.
One-year results from LEADERS FREE presented at TCT. 1-month only DAPT course both significantly safer and more effective than a bare metal stent in High Bleeding Risk (HBR) Patients. 
Enrolment of Biosensors first trial in the USA “BioFreedom USA” was completed. 
Enrolment of LEADERS FREE Japan was completed. 
OCT findings from EGO BioFreedom™ were presented at EuroPCR. 
RUDI FREE began enrolment. The first all comers registry for BioFreedom™ 
Enrolment in LEADERS Free complete: Patient population data presented at EuroPCR. 
Chroma Cobalt-Chromium BMS launched at EuroPCR. 
BioFreedom granted conditional IDE for US-based clinical trial. 
4-year results from BioFreedom FIM study presented at TCT: comparable long-term safety and efficacy to DES demonstrated. 
Launch of Chroma™ our first cobalt chromium bare metal stent. 
e-BioMatrix registry data presented at EuroPCR: confirms safety of BioMatrix over 12 months in ‘real world’ patient population of 5,000. 
BioMatrix NeoFlex gains CE Mark approval. 
BioFreedom gains CE Mark approval. 
First patient enrolled in LEADERS Free, world’s first prospective, randomised double-blind trial employing only a one-month course of DAPT after implantation of active stent. 
Final 5-year results from LEADERS presented at TCT: reduced risk of clinical events vs Cypher Select, associated with reduced risk of VLST. 
Comfortable AMI results published in JAMA: BioMatrix shown to reduce cardiac events in acute MI patients more effectively than a BMS. 
BioMatrix Flex chosen as stent used in GLOBAL LEADERS, largest ever randomised clinical trial involving DES: Aim to enrol 16,000 patients from all-comers population to assess benefits of new antiplatelet regimens. 
LEADERS 4-yr data presented at TCT & published in Lancet; show improved long-term outcomes for BioMatrix Flex compared with durable polymer DES. 
BioFreedom 2-year FIM results presented at TCT: show comparable safety and efficacy to DES. 
Biosensors International acquires remaining 50% of joint venture in China, J W Medical Systems Ltd. 
LEADERS 3-yr data presented at TCT. 
Biosensors International launches BioMatrix Flex™ abluminal biodegradable polymer DES. 
Biosensors International presents 9, 12 months and 24 months LEADERS results showing comparable safety and efficacy to industry leading drug-eluting stent at ESC and TCT congresses. Peer-reviewed article highlighting 9-month LEADERS results published in The Lancet. 
Biosensors receives CE Mark approval for its BioMatrix™ abluminal biodegradable polymer DES and launch across Europe. 
Biosensors International launches PTCA catheters. 
Biosensors Japan receives Japanese Ministry of Health, Labor and Welfare approval for its coronary bare metal S-Stent™. 
Biosensors International makes First-In-Man implantation of its BioFreedom™ polymer-free drug-eluting stent. 
Axxion™ drug-eluting stent receives CE Mark approval for commercialization in the European Union countries. 
Biosensors International receives patent from U.S. Patent and Trademark Office covering the use of anti-restenotic, immunosuppressive drugs in combination with a biodegradable drug-release polymer coating on a stent. 
Biosensors International enters into Asset Purchase and Licensing Agreement with Advanced Cardiovascular Systems, Inc., a subsidiary of Guidant Corporation to utilize Biosensors' biodegradable polymer technology and clinical data generated under the FUTURE I and FUTURE II clinical trials conducted by Biosensors. 
Biosensors International enters into agreement with Terumo Corporation with respect to the manufacturing, supply and distribution of Biosensors’ DES technologies on an exclusive basis in Japan and on a non-exclusive basis elsewhere in the world outside of the U.S. 
Biosensors International acquires Occam International B.V. 
Biosensors International makes its first entry into the interventional cardiology products market with commercialization of its CE Marked S-Stent™ bare metal stent. 
Biosensors International starts development of drug-eluting stents. 
Start of in-house research and development. 
Biosensors International Pte Ltd is founded by Yoh-Chie Lu as a contract manufacturing company for critical care products.